Cefpodoxime is an antibiotic prescribed to treat bacterial infections in various parts of the body including sinus infections.¹

Cefpodoxime comes as a tablet and suspension (liquid) to take by mouth. It is usually taken every 12 hours for 5 to 14 days depending on the condition being treated. Take the tablet with food; the suspension can be taken with or without food. Take cefpodoxime at around the same time every day. Follow the directions on your prescription label carefully and ask your doctor or pharmacist to explain any part you do not understand. Take cefpodoxime exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Shake the suspension well before each use to mix the medication evenly.

You should begin to feel better during the first few days of treatment with cefpodoxime. If your symptoms do not improve or get worse, call your doctor.

Continue to take cefpodoxime until you finish the prescription even if you feel better. If you stop taking cefpodoxime too soon or skip doses, your infection may not be completely treated and the bacteria may become resistant to antibiotics.²

Dosing for cefpodoxime can vary depending on the person. Always follow the prescribed dosage from your provider. Common dosage to treat a sinus infection in adults in 200 milligrams, every 12 hours.³

Symptoms should start to resolve within the first few days of taking cefpodoxime. If you do not see any improvement, please contact your provider.⁴

Cefpodoxime should be out of your system within 22 hours of your final dose.⁵

It is important to continue to take cefpodoxime until you finish the prescription, even if you feel better. If you stop taking cefpodoxime too soon or skip doses, your infection may not be completely treated, and the bacteria may become resistant to antibiotics.⁶

Cefpodoxime is available without insurance for $50 per treatment (14 tablets) through RedBox Rx. Start an online consultation to see if cefpodoxime is right for you.

• Tell your doctor and pharmacist if you are allergic to cefpodoxime; any other cephalosporin antibiotic such as cefaclor, cefadroxil,cefazolin (Ancef, Kefzol), cefdinir, cefditoren (Spectracef), cefepime (Maxipime), cefixime (Suprax), cefotaxime (Claforan), cefotetan, cefoxitin (Mefoxin), cefprozil, ceftaroline (Teflaro), ceftazidime (Fortaz, Tazicef, in Avycaz), ceftibuten (Cedax), ceftriaxone (Rocephin), cefuroxime (Zinacef) and cephalexin (Keflex);penicillin antibiotics; or any other medications. Also tell your doctor if you are allergic to any of the ingredients in cefpodoxime tablets or suspension.Ask your pharmacist for a list of the ingredients.

• Tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: antacids (Maalox, Mylanta, others), cimetidine, colistimethate (Coly-Mycin M), diuretics ('water pills'), famotidine (Pepcid), gentamicin, kanamycin, neomycin (Neo-Fradin), nizatidine (Axid), polymixin B, probenecid (Probalan), ranitidine (Zantac), streptomycin, tobramycin. and vancomycin (Vancocin). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.

• Tell your doctor if you have or have ever had gastrointestinal disease (GI; affecting the stomach or intestines), especially colitis (condition that causes swelling in the lining of the colon [large intestine]), or kidney disease.

• Tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking cefpodoxime, call your doctor.

• If you have phenylketonuria (PKU, an inherited condition in which a special diet must be followed to prevent damage to your brain that can cause severe intellectual disability), you should know that cefpodoxime suspension is sweetened with aspartame that forms phenylalanine.⁷

If you miss a dose, take it as soon as you remember. If it is close to the time for your next dose, just take the next dose and continue as instructed. Do not double up on doses.⁸

Common side effects of cefpodoxime include:⁹

• Nausea

• Vomiting

• Diarrhea

• Stomach pain

• Swelling, redness, irritation, burning, or itching of the vagina

• White vaginal discharge

• Headache

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store the tablets at room temperature and away from light and excess heat and moisture (not in the bathroom). Keep liquid medicine in the refrigerator, tightly closed, and dispose of any unused medication after 14 days.

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach.¹⁰

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Symptoms of overdose may include the following:¹¹

• nausea

• vomiting

• diarrhea

• stomach pain

Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to check your response to cefpodoxime.

Before having any laboratory test, tell your doctor and the laboratory personnel that you are taking cefpodoxime.

If you are diabetic and test your urine for sugar, use Clinistix or TesTape (not Clinitest) to test your urine while taking this drug.

Do not let anyone else take your medication. Your prescription is probably not refillable. .

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.¹²

Brand names for cefpodoxime include:¹³

• Banan^®

• Vantin^®

RedBox Rx offers a variety of medication treatments for sinus headaches and sinus infections including:

• Amoxicillin (Amoxil®)

• Amoxicilin/Clavulanate (Augmentin®)

• Doxycycline (Vibramycin®)

• Fluticasone Nasal Spray (Flonase®)

• Guaifenesin (Mucinex®)

• Oxymetazoline (Afrin®)

• Levocetirizine (Xyzal®)

• Levofloxacin (Levaquin®)

• Saline spray for the nose

1. Mayo Clinic

2. National Library of Medicine

3. Mayo Clinic

4. National Library of Medicine

5. Drugs.com

6. National Library of Medicine

7. National Library of Medicine

8. National Library of Medicine

9. National Library of Medicine

10. National Library of Medicine

11. National Library of Medicine

12. National Library of Medicine

13. National Library of Medicine