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  • An illustration of a person affected by melasma.

Affordable melasma and dark spot treatment from home. 

Treat melasma, dark spots and hyperpigmentation from the comfort of your home – with no wait. We offer FDA-approved, clinically proven melasma prescriptions at affordable prices with fast, free shipping. Get started with a quick and easy online assessment.

  • Low-cost $20 telehealth consult.
  • Medications starting at $20 per month.
  • Free standard shipping or expedited/overnight available.
  • HSA and FSA eligible.

Compare Melasma Treatment Prices

See how we stack up against competitors on costs to treat melasma, dark spots and hyperpigmentation. Not only do we offer transparent, low prices on medications, we charge only $20 for an online consult for melasma with one of our experienced, U.S.-licensed medical providers.

Brand Tretinoin Cream Costs

RedBox Rx

$20/month billed as $60/3 months

Hers®

$29/month

WISP

$25/month billed as $75/3 months

NURX

$30/month billed as $90/3 months + $30 consultation fee

Agency

$40-$65/month

Apostrophe

$25/month billed as $75/3 months

About Melasma

Melasma is a skin condition that causes hyperpigmentation and dark spots — primarily on the face. It can be managed with a combination of sun protection and topical treatments.

  • Melasma is a common skin condition that causes dark spots and patches on the skin, most often on the face. It occurs nine times more often in women than in men.1 

  • With the condition melasma, exposure to sunlight causes skin to produce more melanin pigments, causing dark spots. Pregnancy or hormonal birth control is the most common cause of melasma in women. Other causes of melasma include:

    • Genetics.

    • Hormones, particularly the female hormones estrogen and progesterone.

    • Thyroid disease.

  • The most common places for melasma to appear are on the cheeks, chin, nose bridge, forehead and above the upper lip.3 For some people, darker pigmentation can occur on the upper lip and resembles a mustache.4

  • Melasma is not physically harmful. Even though melasma reacts to sun exposure, there is no evidence to suggest that the condition increases risk of skin cancer. In fact, people with melasma have lower rates of skin cancer overall.5

    However, some people with melasma can experience psychological issues or a poorer quality of life because of perceptions of their appearance.6

  • Melasma commonly appears on the face. Less commonly it can appear on the arms, neck or other parts of the body.7

  • Hyperpigmentation refers to any discoloration of the skin, regardless of the cause. Melasma is a type or cause of hyperpigmentation.8

  • Sunspots, also known as age spots, dark spots or liver spots, are small areas of hyperpigmentation on the skin caused by ultraviolet light (UV) exposure to the skin.9 Melasma can be triggered by sun; however, the underlying cause can be hormonal or genetic.10

    Sunspots occur most often in people over age 50 but can occur in younger people.11 Melasma occurs most commonly in women in their reproductive years.12

  • Yes, melasma commonly occurs during pregnancy. Research shows that melasma is present in approximately 15-50% of pregnant patients.13 

  • Melasma is a photosensitive condition that is exacerbated by exposure to the sun. Therefore, regular use of UV + VL broad-spectrum sunscreen can be used as a preventive treatment for melasma.14 

  • There is currently no cure for melasma. However, dark spots can be reduced or prevented by limiting sun exposure. Also, hyperpigmentation can be lightened or reversed by using topical or oral medications.15 

  • Melasma can often go away on its own. Patients that avoid sun exposure and utilize topical treatments can see reversal of melasma in a few months' time. Progress is typical gradually and requires patience.16

    For example, one clinical trial showed that 68% of participants experienced a significant improvement in melasma marks after 40 weeks (approximately 10 months) of daily application of tretinoin.17 

Melasma Medication Options

We feel our best when we look our best. RedBox Rx has a variety of prescription treatments to help women and men reduce the signs of melasma and aging like fine lines, wrinkles and dark spots.

  • RedBox Rx Hydroquinone 4% Cream Tube
    Hydroquinone cream, treats blemishes and dark spots

    Hydroquinone cream lightens dark patches on skin (such as dark spots, melasma, hyperpigmentation) by blocking the process in the skin that leads to discoloration. Visit with one of our U.S. licensed medical providers online to see if a hydroquinone prescription is right for you.

    Starting at: $20 per month - 1 28.35 g tube (billed and shipped every 3 months)

  • RedBox Rx Azelaic Acid 15% Gel Tube - 50 g
    Azelaic Acid 15% Gel (Generic Finacea®)

    Treat rosacea or hyperpigmentation such as melasma or dark spots with azelaic acid 15% gel, an FDA-approved prescription-strength topical medication. While azelaic acid 15% gel is not available over the counter, RedBox Rx prescribes this medication through convenient online doctor consultations.

    Starting at: $20 per month – 50 g tube (90-day supply required) (auto refills every 90 days)

  • Tretinoin 0.1%  Cream 45 g Tube
    Tretinoin Cream (Generic Retin-A®)

    Your skin is unique to you and how you treat it is just as unique. Many times, that means prescription strength, clinically proven ingredients. One of those ingredients could be tretinoin to reduce the appearance of acne and the visual signs of aging. Let us help customize your skincare plan today.

    Starting at: $20 per month - 1 45 g tube (billed and shipped every 3 months)

  • RedBox Rx Tazarotene 0.1% cream - 30 g
    Tazarotene 0.1% Cream (Generic Tazorac®)

    Treat acne or reduce fine lines and wrinkles with tazarotene 0.1% cream, an FDA-approved prescription-strength topical retinoid. While tazarotene 0.1% cream is not available over the counter, RedBox Rx prescribes this medication through convenient online doctor consultations.

    Starting at: $75 for 30 g tube (45-day supply) (auto refills every 45 days)

  • Adapalene Gel 0.3% Tube
    Adapalene Gel (Generic Differin®)

    Adapalene is an FDA-approved medication that has shown promising results in reducing acne and the appearance of fine lines and wrinkles, as well as improving skin tone and texture. Our U.S. licensed medical professionals can help you determine if a prescription is a good addition to your acne or anti-aging skincare regimen.

    Starting at: $20 per month - 1 45 g tube

Hydroquinone Cream 4%

75%

75% of study participants saw an improvement in melasma with hydroquinone topical treatment.

Sorry, we’re closed for today. Our U.S. licensed medical providers are available daily 7 a.m. to 9 p.m. CST via live video visit. We look forward to serving you soon. Email us anytime at [email protected].

What Our Patients Are Saying

  • Easy to use and quickly responds. I really need this treatment for my skin and they provide me, and cover my necessities.

    Gloria A.
  • Very easy and convenient to connect with Redbox. No long wait times and easy to talk to the professional. I would recommend for anyone having to wait several months to see a dermatologist.

    Patricia H.
  • For context, I wanted to start topical tretinoin so if you need other types of prescriptions, I can’t speak to that. Questions were very thorough, and I got a response quickly. My medication was prescribed and in my mailbox in under five days.

    Paige E.

Melasma Treatment FAQs 

  • There are a variety of treatments available for melasma and dark spots. Some treatments will help prevent dark spots from forming and others will help lighten dark spots that have already formed. Here is an overview of some of the types of melasma treatments.

    Sunscreen

    Limiting sun exposure and using sunscreen is one of the best treatments for melasma. Studies show that broad-spectrum tinted sunscreens with iron oxide are effective at lowering pigment production in the skin in melasma patients because they block visible light and UVA/UVB rays.18

    Topical Skin Treatments

    Dark spots caused by melasma can be lightened using topical skin-lightening medications, including hydroquinone, azelaic acid, kojic acid, niacinamide, cysteamine, rucinol and tranexamic acid. They reduce the pigment production, inflammation and excess blood cells that contribute to melasma dark spots.19

    Chemical Peels

    If limiting sun exposure and topical treatments fail, melasma can be treated with chemical skin peels. Using glycolic or salicylic acid-based compounds, a chemical skin peel can help increase skin cell turnover. The results of a chemical peel can be unpredictable and sometimes result in adverse effects like scarring or increased hyperpigmentation.20

    Lasers

    Laser treatment can destroy the pigment in skin to lighten melasma spots. However, the risk is considerable for relapse post-treatment.21 In some cases, a laser treatment can actually worsen the melasma condition.22

  • Topical treatments for melasma must be continued for several months before noticeable changes may occur.28 In some studies, uses of topical treatments for hyperpigmentation saw noticeable results within eight to 12 weeks.29 Another study showed significant results after 40 weeks of daily tretinoin use, so it can vary on the individual and treatment.30

  • If you are looking for an over-the-counter melasma treatment, dermatologists recommend finding topical products with alpha hydroxy, kojic acids or retinols. These active ingredients can aid in cell rejuvenation.31

    Alpha-hydroxy acid or glycolic acid has good clinical effectiveness for treating melasma when it is combined with hydroquinone.32 Alpha-hydroxy on its own may need more research.33

    Kojic Acid reduced melasma pigmentation in 52% of study participants.34

    Retinols have been shown to be effective in treating melasma when combined with hydroquinone.35 However, over-the-counter retinol may need more research to support its effectiveness as a solo treatment.

    Most over-the-counter melasma treatments are considered cosmetics and are not required to have FDA approval.36 There is currently a lack of research to prove nonprescriptions effectiveness in treating hyperpigmentation from melasma.37

  • Telehealth providers, like RedBox Rx, allow you to connect with a licensed provider of dermatological services anywhere you have an internet connection. If prescribed, we can ship prescription treatment for melasma to all 50 U.S. states. Start an online consult now.

How RedBox Rx Works

  • Select how you want to treat your condition.

    Choose either a specific treatment or condition. Then fill out a quick online assessment about your health history and current concerns.

  • Get your personalized treatment plan.

    After a review by an experienced medical provider, you will receive recommended treatment options so you can complete the prescription order for your medication.

  • Prescriptions delivered right to your door.

    Enjoy free, fast shipping on all prescribed treatments from our U.S. licensed online pharmacy.

RedBox Rx Prescription Melasma Medicine Bottles

Why Choose RedBox Rx

Wide selection, easy process and low prices.

  • No membership or subscription fees.
  • Low-cost $20 telehealth consult with licensed medical provider.
  • Medications start at $20 per month (with purchase of three-month supply).
  • Confidential, private and secure.
  • Free standard shipping or expedited/overnight available.

Sorry, we’re closed for today. Our U.S. licensed medical providers are available daily 7 a.m. to 9 p.m. CST via live video visit. We look forward to serving you soon. Email us anytime at [email protected].

From the RedBox Rx Blog

Hair & Skin

Tretinoin (Retin-A®) Cream vs. Gel: What’s the Difference?

May 01, 2023 | 2 Min Read

Discover the differences between tretinoin (Retin-A®) cream and gel, two topical solutions used to treat acne and signs of aging. Learn which one is right for you and what you can expect when using tretinoin.
Hair & Skin

Tretinoin (Retin-A®) and Hydroquinone: In-Depth Overview

Jun 07, 2023 | 1 Min Read

Medical providers have long trusted tretinoin and hydroquinone for their remarkable ability to improve common skin issues. But what sets these two apart? Can they be used together? And what about their side effects? Explore our in-depth overview.
Hair & Skin

Tazarotene (Tazorac®) vs. Tretinoin (Retin-A®): What’s Best for Aging & Wrinkles?

May 02, 2024 | 3 Min Read

Tazarotene (Tazorac®) and tretinoin (Retin-A®) are two clinically proven topical anti-aging treatments. Learn about their effectiveness, side effects and costs to make an informed decision about your skincare.

RedBox Rx is here when you need us with out-of-the-box personalized care.

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